The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival
N. Dieguez-Martinez, S. Espinosa-Gil, G. Yoldi, E. Megias-Roda, I. Bolinaga-Ayala, M. Vinas-Casas, I. Domingo-Orti, H. Perez-Montoyo, J. R. Bayascas, E. Colas, X. Dolcet, J. M. Lizcano
This study identifies the ERK5/NF-κB pathway as a driver of endometrial cancer proliferation and survival, showing that its inhibition sensitizes tumors to chemotherapy and reduces xenograft growth.
bioRxiv · May 31, 2022Cancer Biology