Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2
J. A. Patino-Galindo, I. Filip, R. Chowdhury, C. D. Maranas, P. K. Sorger, M. AlQuraishi, R. Rabadan
This paper identifies an ancestral recombination event in the RBD of SARS-CoV and SARS-CoV-2 that increased hACE2 binding affinity, suggesting SARS-like viruses may have pandemic potential.
bioRxiv · Feb 10, 2020 · PreprintEvolutionary Biology