Cancer BiologybioRxiv
Lymphatic-Preserving Treatment Sequencing with Immune Checkpoint Inhibition Unleashes cDC1-Dependent Antitumor Immunity in HNSCC
R. Saddawi-Konefka, A. O'Farrell, F. Faraji…·J. S. Gutkind
This study shows that lymphatic-preserving treatment sequences enhance cDC1-dependent antitumor immunity in HNSCC by avoiding lymphablation, which compromises ICI response.
DOI 10.1038/s41467-022-31941-w