I. Hastings

Insecticide resistance management strategies for public health control of mosquitoes exhibiting polygenic resistance: a comparison of sequences, rotations, and mixtures.

This paper compares insecticide resistance management strategies for mosquitoes with polygenic resistance, finding that full-dose mixtures extend strategy lifespan more than sequences or rotations.

Evaluating rotations as a strategy to delay the evolution of insecticide resistance in vectors of human diseases.

This study evaluates insecticide rotation strategies in silico to delay resistance evolution in disease vectors, finding small and unpredictable advantages over sequential deployment.

Should deep-sequenced amplicons become the new gold-standard for analysing malaria drug clinical trials?

This paper evaluates deep sequenced amplicons (AmpSeq) as a method for molecular correction in malaria drug trials, finding it improves drug failure rate detection compared to current methods.

Incorporating genetic selection into individual-based models (IBMs) of malaria and other infectious diseases.

This paper describes how to incorporate genetic selection into individual-based models of infectious diseases, identifying strategies and recommendations for simulating mutation spread and control effectiveness.

Evaluating artesunate-amodiaquine deployment, efficacy and safety: an in silico pharmacological model

This study uses a pharmacological model to compare the efficacy, effectiveness, and safety of AS-AQ fixed dose combination and non-fixed formulations in different treatment scenarios.