Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein
M. A. Simon, I. Iordanov, A. Szollosi, L. Csanady
The paper estimates the non-hydrolytic closing rate of WT CFTR by comparing it to mutants with disrupted ATP hydrolysis, revealing how specific mutations affect this rate.
bioRxiv · Jul 16, 2023Biophysics