XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures
K. Ellwanger, C. Arnold, S. Briese, I. Kienes, J. Pfannstiel, T. A. Kufer
This study shows that XIAP prevents RIPK2 from forming insoluble complexes, which is necessary for NOD1-dependent NF-κB activation.
bioRxiv · Feb 8, 2019Immunology