Native extracellular matrix probes to target patient- and tissue- specific cell-microenvironment interactions by force spectroscopy
H. Holuigue, L. Nacci, P. Di Chiaro, M. Chighizola, I. Locatelli, C. Schulte, M. Alfano, G. R. Diaferia, A. Podesta
The paper develops native ECM AFM probes to study cell-microenvironment interactions, showing they preserve ECM complexity and reveal region-specific adhesion patterns in bladder cancer cells.
bioRxiv · Dec 2, 2022 · PreprintBiophysics