Author

I. M. Vedel

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Prestel· 1 shared B. B. Kragelund· 1 shared G. H. J. Peters· 1 shared H. Stark· 1 shared N. T. Skawinska· 1 shared P. Harris· 1 shared Z. Zhang· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Prestel

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1 paper

Recent·Most cited

Structural characterization of human tryptophanhydroxylase 2 reveals L-Phe as the superior regulatorydomain ligand relevant for serotonin biosynthesis

I. M. Vedel, A. Prestel, Z. Zhang, N. T. Skawinska, H. Stark, P. Harris, B. B. Kragelund, G. H. J. Peters

This study determines the structure of TPH2's regulatory domain with L-Phe and shows it is a better ligand than L-Trp, revealing dynamic behavior in the tetramer.

bioRxiv · Sep 20, 2022 · PreprintBiophysics