BiophysicsbioRxivPreprint
Structural characterization of human tryptophanhydroxylase 2 reveals L-Phe as the superior regulatorydomain ligand relevant for serotonin biosynthesis
I. M. Vedel, A. Prestel, Z. Zhang…·G. H. J. Peters
This study determines the structure of TPH2's regulatory domain with L-Phe and shows it is a better ligand than L-Trp, revealing dynamic behavior in the tetramer.
DOI 10.1101/2022.09.20.508773