Claudin-4, a core component of the tight-junctional complex along the collecting system, is induced in nephrotic syndrome
V. Olivier, A. SASSI, G. Arnoux, R. Chambrey, I. Monnay, A. Chassot, K. Udwan, E. Dizin, J. M. Rutkowski, L. Cheval, G. Crambert, C. A. Wagner, A. Doucet, D. Eladari, S. Moll, , S. K Ramakrishnan
This study shows claudin-4 expression increases in nephrotic syndrome, suggesting a shift from transcellular to paracellular chloride transport in the kidney collecting system.
bioRxiv · Jun 1, 2022 · PreprintPhysiology