Discovery and pharmacological characterization of nanobodies acting as potent positive allosteric modulators of the calcium-sensing receptor
I. Mos, T. Zögg, A. Wohlkönig, A. M. H. Egholm, S. N. Rahman, E. Pardon, J. Steyaert, H. Bräuner-Osborne, J. M. Mathiesen
This study identifies and characterizes nanobodies that act as potent positive allosteric modulators of the calcium-sensing receptor, offering new tools for research and potential therapeutic applications.
bioRxiv · Jul 8, 2024 · PreprintBiochemistry