mTOR pathway inhibition stimulates pharmacologically induced nonsense suppression
A. Wittenstein, M. Caspi, I. Rippin, O. Elroy-Stein, H. Eldar-Finkelmn, S. Thoms, R. Rosin-Arbesfeld
This study shows that inhibiting the mTOR pathway enhances antibiotic-mediated readthrough of nonsense mutations, offering a new therapeutic strategy for genetic diseases.
bioRxiv · Aug 31, 2022 · PreprintCell Biology