Cryo-OrbiSIMS for 3D molecular imaging of a bacterial biofilm in its native state
J. Zhang, J. Brown, D. Scurr, A. Bullen, K. MacLellan-Gibson, P. Williams, M. R. Alexander, K. R. Hardie, I. S. Gilmore, P. Rakowska
This paper introduces Cryo-OrbiSIMS for 3D molecular imaging of bacterial biofilms, revealing the spatial distribution of quorum sensing molecules and membrane components in Pseudomonas aeruginosa.
bioRxiv · Nov 30, 2019Microbiology