Author

I. Shams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Evolutionary Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Avivi· 1 shared A. Bicker· 1 shared A. de la Cruz· 1 shared A. Hinojo-Perez· 1 shared A. N. Davydov· 1 shared D. A. Miskevich· 1 shared D. B. Staroverov· 1 shared D. Bolotin· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperEvolutionary Biology

A. Avivi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lipophilic compounds restore wt function of neurodevelopmental-associated KCNQ3 mutations.

M. A. Edmond, A. Hinojo-Perez, M. Efrem, Y.-C. Lin, I. Shams, S. Hayoz, A. de la Cruz, M. E. P. rodriguez, M. Diaz-Solares, D. M. Dykxhoorn, Y. Luo, R. B. Soria

The paper investigates how two KCNQ3 mutations impair channel function and shows that polyunsaturated fatty acids can restore wild-type function in these mutations.

bioRxiv · Mar 13, 2024 · PreprintBiophysics

Adaptation of the Spalax galili transcriptome to life under hypoxia may hold a key to a complex phenotype including longevity and cancer resistance

G. Poetzsch, L. Jelacic, A. Bicker, M. Balling, L. Hellmann, L. Dammer, M. Andrade, I. Shams, A. Avivi, T. Hankeln

This study compares transcriptomic responses to hypoxia in Spalax and rat, identifying gene expression patterns linked to longevity and cancer resistance.

bioRxiv · Aug 1, 2023 · PreprintEvolutionary Biology

Intracellular reactive oxygen species (intraROS)-aided localized cell death contributing to immune responses against wheat powdery mildew pathogen

Y. Li, R. Roychowdhury, L. Govta, S. Jaiwar, Z.-Z. Wei, I. Shams, T. Fahima

The paper quantifies intraROS and apoROS accumulation in wheat infected by Bgt, showing that intraROS contributes to localized cell death in NLR R gene lines, while unconventional R genes show reduced intraROS responses.

bioRxiv · Oct 6, 2022Pathology

T cell immunity does not age in a long-lived rodent species

M. Izraelson, T. O. Nakonechnaya, A. N. Davydov, M. A. Dronina, D. A. Miskevich, I. Z. Mamedov, L. N. Barbashova, M. Shugay, D. Bolotin, D. B. Staroverov, E. Y. Kondratyuk, E. A. Bogdanova, S. Lukyanov, I. Shams, O. V. Britanova, D. M. Chudakov

This study compares T cell receptor diversity across species, finding that long-lived rodents maintain stable TCR diversity with age, unlike humans and mice.

bioRxiv · Sep 5, 2018Immunology