Author

O. V. Britanova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:mouse· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

D. M. Chudakov· 4 shared D. A. Price· 2 shared D. B. Staroverov· 2 shared K. L. Miners· 2 shared K. Ladell· 2 shared M. Shugay· 2 shared T. O. Nakonechnaya· 2 shared V. V. Kriukova· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersImmunology

D. M. Chudakov

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4 papers

Recent·Most cited

Repertoire-based mapping and time-tracking of helper T cell subsets in scRNA-Seq

D. K. Lukyanov, V. V. Kriukova, K. Ladell, I. A. Shagina, D. B. Staroverov, B. Minasian, A. S. Fedosova, P. Shelyakin, O. N. Suchalko, A. Komkov, K. A. Blagodatskikh, K. L. Miners, O. V. Britanova, A. Franke, D. A. Price, D. M. Chudakov

This paper introduces TCR-Track, a method to map and track helper T cell subsets in scRNA-Seq data, revealing their clonal relationships and functional programs over time.

bioRxiv · Oct 24, 2023Immunology

Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism

T. O. Nakonechnaya, B. Moltedo, E. V. Putintseva, S. Leyn, D. A. Bolotin, O. V. Britanova, M. Shugay, D. M. Chudakov

This study investigates Treg cell responses to different antigenic challenges using TCR repertoire analysis, revealing challenge-specific and tissue-specific clonal expansions and plasticity.

bioRxiv · Jun 15, 2023Immunology

Inhibitory IL-10-producing CD4+ T cells develop in a T-bet-dependent manner and facilitate cytomegalovirus persistence via coexpression of arginase-1

M. Clement, K. Ladell, K. L. Miners, M. Marsden, L. Chapman, A. Cardus-Figueras, J. Scott, R. Andrews, S. Clare, V. V. Kriukova, K. R. Lupyr, O. V. Britanova, D. R. Withers, D. M. Chudakov, S. A. Jones, , I. Humphreys

The paper identifies IL-10-producing CD4+ T cells that develop via T-bet dependence and Arg1 coexpression, promoting cytomegalovirus persistence.

bioRxiv · Jan 25, 2022Immunology

T cell immunity does not age in a long-lived rodent species

M. Izraelson, T. O. Nakonechnaya, A. N. Davydov, M. A. Dronina, D. A. Miskevich, I. Z. Mamedov, L. N. Barbashova, M. Shugay, D. Bolotin, D. B. Staroverov, E. Y. Kondratyuk, E. A. Bogdanova, S. Lukyanov, I. Shams, O. V. Britanova, D. M. Chudakov

This study compares T cell receptor diversity across species, finding that long-lived rodents maintain stable TCR diversity with age, unlike humans and mice.

bioRxiv · Sep 5, 2018Immunology