PhysiologybioRxiv
Knockout of Hsp70 genes significantly affects locomotion speed and gene expression in leg skeletal muscles of Drosophila melanogaster
P. A. Makhnovskii, I. V. Kukushkina, N. S. Kurochkina, D. V. Popov
This study shows that knocking out six Hsp70 genes in Drosophila reduces locomotor speed and disrupts adaptation to exercise training, with changes in leg muscle gene expression.
DOI 10.1152/physiolgenomics.00143.2023