IL-17 activation undermines longevity and stress tolerance by inhibiting a protective transcriptional network
Q. Lu, I. Vladareanu, L. Zhao, L. Nilsson, J. Henriksson, C. Chen
This study shows that IL-17 overactivation in C. elegans reduces lifespan and stress tolerance by inhibiting a protective transcriptional network involving NHR-49 and MDT-15.
bioRxiv · Jan 13, 2023 · PreprintCell Biology