I. Y.-L. Chen

Personalized biventricular mechanics and sensitivity to model morphology

The paper develops a patient-specific cardiac mechanics model using clinical data and evaluates its performance against simplified models, finding that truncation significantly affects results.

Effects of Left Atrial Wall Thickness on Myocardial Mechanics and Blood Dynamics using Multiscale Modeling

This study uses multiscale modeling to show that left atrial wall thickness significantly affects myocardial stresses and oscillatory shear, more than other factors like cavity volume or displacement.

Personalized Multiscale Modeling of Left Atrial Mechanics and Blood Flow

This paper develops a personalized multiscale model of left atrial mechanics and blood flow to simulate deformation and hemodynamics using patient-specific data.

Intrinsic Phenotypic Differences, Not Hemodynamic Shear, Associate with Cusp-Specific Remodeling in Aortic Valve Disease

Immunosuppression Drugs Exhibit Differential Effects on Endothelial Cell Function

This study examines how different immunosuppression drugs affect endothelial cell function using human-derived cells, finding that sirolimus impacts multiple functions while tacrolimus mainly affects nitric oxide release.

Cardioprotection by Poloxamer 188 is Mediated through Increased Endothelial Nitric Oxide Production

This study shows that Poloxamer 188 protects against ischemia/reperfusion injury by increasing endothelial nitric oxide production in both cell and rat models.