Author

Demetris Yannopoulos

University of MinnesotaORCID 0000-0002-7131-2015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Bhairab N. SinghiD· 1 shared Claudius BalzeriD· 1 shared Daniel J. GarryiD· 1 shared Detlef ObaliD· 1 shared Gaoxian CheniD· 1 shared Hunter F. DouglasiD· 1 shared I. Y.-L. CheniD· 1 shared Joshua W. M. TheiseniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Bhairab N. SinghORCID

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2 papers

Recent·Most cited

Cardioprotection by Poloxamer 188 is Mediated through Increased Endothelial Nitric Oxide Production

Gaoxian Chen, Hunter F. Douglas, Zhu Li, William J. Cleveland, Claudius Balzer, Demetris Yannopoulos, I. Y.-L. Chen, Detlef Obal, Matthias L. Riess

This study shows that Poloxamer 188 protects against ischemia/reperfusion injury by increasing endothelial nitric oxide production in both cell and rat models.

Scientific Reports · Apr 30, 2025Peer-reviewedPharmacology & Toxicology

A novel algorithm for the collective integration of single cell RNA-seq during embryogenesis

Wuming Gong, Bhairab N. Singh, Pruthvi Shah, Satyabrata Das, Joshua W. M. Theisen, Sunny Sun-Kin Chan, Michael Kyba, Mary G. Garry, Demetris Yannopoulos, Wei Pan, Daniel J. Garry

This paper introduces a novel algorithm to integrate heterogeneous temporal scRNA-seq datasets and reconstruct lineage trajectories, identifying Ebf1 as a key transcription factor for mouse endothelial development.

bioRxiv · Feb 7, 2019 · PreprintBioinformatics