Celloscope: a probabilistic model for marker-gene-driven cell type deconvolution in spatial transcriptomics data
Agnieszka Geras, Shadi Darvish Shafighi, Kacper Domżał, Igor Filipiuk, Alicja Rączkowska, Paulina Szymczak, Hosein Toosi, Leszek Kaczmarek, Łukasz Koperski, Jens Lagergren, Dominika Nowis, Ewa Szczurek
Celloscope deconvolves cell types in spatial transcriptomics data using marker genes, outperforming existing methods and accurately identifying brain structures and immune infiltrates.
Genome biology · May 17, 2023Peer-reviewedBioinformatics