Biophysical cartography of the native and human-engineered antibody landscapes quantifies the plasticity of antibody developability
Habib Bashour, Eva Smorodina, Matteo Pariset, Jahn Zhong, Rahmad Akbar, Maria Chernigovskaya, Khang Lê Quý, Igor Snapkow, Puneet Rawat, Konrad Krawczyk, Geir Kjetil Sandve, Jose Gutierrez‐Marcos, Daniel Nakhaee-Zadeh Gutierrez, Jan Terje Andersen, Victor Greiff
The paper quantifies the plasticity of antibody developability by analyzing sequence and structure-based parameters in natural and human-engineered antibodies.
Communications Biology · Jul 31, 2024Peer-reviewedBioinformatics