Jahn Zhong

PEPE: Scalable extraction of multi-modal protein language model representations

PEPE efficiently extracts multimodal protein embeddings from language models, enabling scalable and memory-efficient generation of large embedding datasets for downstream biological tasks.

Quantitative mapping of antigen specificity in adaptive immune repertoire embedding spaces

The paper quantitatively maps antigen specificity in immune repertoire embedding spaces, showing distinct regions for different antigen-specific sequences.

Biophysical cartography of the native and human-engineered antibody landscapes quantifies the plasticity of antibody developability

The paper quantifies the plasticity of antibody developability by analyzing sequence and structure-based parameters in natural and human-engineered antibodies.