Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma
Pranvera Sadiku, Alejandro J. Brenes, Rupert Laurenz Mayer, Leila Reyes, Patrícia Coelho, Gabi van Stralen, Ailiang Zhang, Manuel A. Sánchez-García, Emily Watts, Imran Liaquat, Andrew J.M. Howden, Ikeoluwa Adekoya, Anuka Boldbaatar, Allan MacRaild, Sarah Risbridger, , Sarah R. Walmsley
The paper uses single cell proteomic analysis to identify distinct functional states of neutrophils in human glioblastoma, revealing clusters with pathogenic and anti-tumorigenic properties not detectable by scRNA-seq.
Nature Communications · Dec 15, 2025Peer-reviewedImmunology