Protein codes promote selective subcellular compartmentalization
Henry R. Kilgore, Itamar Chinn, Peter G. Mikhael, Ilan Mitnikov, Catherine Van Dongen, G. Zylberberg, Lena K. Afeyan, Salman F. Banani, Susana Wilson Hawken, Tong Ihn Lee, Regina Barzilay, Richard A. Young
This study introduces ProtGPS, a protein language model that predicts subcellular compartment localization and identifies mutations affecting this process.
Science · Feb 6, 2025Peer-reviewedBiochemistry