Author

Tong Ihn Lee

Whitehead Institute for Biomedical ResearchORCID 0000-0003-1847-0898Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Approach:transformer / foundation model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Richard A. YoungiD· 2 shared Salman F. BananiiD· 2 shared Susana Wilson Hawken· 2 shared Adrienne VancuraiD· 1 shared Anne L. RobertsoniD· 1 shared Catherine Van DongeniD· 1 shared G. Zylberberg· 1 shared Hailey ErbiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Richard A. YoungORCID

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2 papers

Recent·Most cited

BiochemistrySciencePeer-reviewedFeb 6, 2025

Protein codes promote selective subcellular compartmentalization

Henry R. Kilgore, Itamar Chinn, Peter G. Mikhael…·Richard A. Young

This study introduces ProtGPS, a protein language model that predicts subcellular compartment localization and identifies mutations affecting this process.

105 citationstop 1%

humanprotein sequence

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Molecular BiologyMolecular CellPeer-reviewedJul 1, 2023

Transcription factors interact with RNA to regulate genes

Ozgur Oksuz, Jonathan E. Henninger, Robert Warneford-Thomson…·Richard A. Young

The paper identifies RNA-binding as a common feature of transcription factors, showing it contributes to gene regulation and is conserved in vertebrates.

275 citationstop 1%

𝕏 PostBluesky