A Unique Type V CRISPR-Cas System Encoded by a Group of Thermus Viruses
Anna B. Trofimova, Alina O. Demkina, Sergey Shmakov, Alexei Livenskyi, Marina V. Serebryakova, Aleksandr A. Dmitriev, Ilya D. Rubinshteyn, Konstantin Severinov, Matvey V. Kolesnik
The paper identifies and characterizes a novel type V CRISPR-Cas system, Cas12r-CRISPR, encoded by Lalka phages in Thermus bacteria, showing its role in targeting mobile genetic elements.
bioRxiv · Apr 21, 2026 · PreprintMolecular Biology