Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis
Anahita Ofoghi, Stefan Kotschi, Imke L. Lemmer, Daniel Thomas Haas, Nienke Willemsen, Batoul Bayer, Anna Jung, Sophie Möller, Stefanie Haberecht-Müller, Elke Krüger, Natalie Krahmer, Alexander Bartelt
This study shows that DDI2 activates NFE2L1 to protect cells from ferroptosis by regulating the ubiquitin-proteasome system.
Cell Death and Differentiation · Oct 9, 2024Peer-reviewedMolecular Biology