Longitudinal Metabolomic Profiling of Biogenic Amines in Plasma and CSF, and Their Correlation, Reveals Sex-Specific and Age Changes in TgF344 Alzheimer's Disease Transgenic and Wildtype Rats
Chunyuan Yin, Imke Nelen, Amy C. Harms, Richard D. Hartman, Sabine Bos, Charlotte Nijgh-van Kooij, Thomas Hankemeier, Alida S. D. Kindt, Elizabeth C. M. de Lange
The paper analyzes longitudinal metabolomic changes of biogenic amines in plasma and CSF of TgF344 AD rats and WT controls, revealing sex- and age-specific differences.
Fluids and Barriers of the CNS · May 9, 2026Peer-reviewedSystems Biology