Author

Chunyuan Yin

Leiden UniversityORCID 0000-0002-4017-9389Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 3 Assay:metabolomics· 3 Approach:statistical model· 3 Organism:rat· 2 Organism:human· 1

Frequent Co-Authors

Elizabeth C. M. de LangeiD· 3 shared Thomas HankemeieriD· 3 shared Alida S. D. KindtiD· 2 shared Amy C. HarmsiD· 2 shared Alida Kindt· 1 shared Charlotte Nijgh-van Kooij· 1 shared Colette BlachiD· 1 shared Imke Nelen· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersSystems Biology

Elizabeth C. M. de LangeORCID

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3 papers

Recent·Most cited

Longitudinal Metabolomic Profiling of Biogenic Amines in Plasma and CSF, and Their Correlation, Reveals Sex-Specific and Age Changes in TgF344 Alzheimer's Disease Transgenic and Wildtype Rats

Chunyuan Yin, Imke Nelen, Amy C. Harms, Richard D. Hartman, Sabine Bos, Charlotte Nijgh-van Kooij, Thomas Hankemeier, Alida S. D. Kindt, Elizabeth C. M. de Lange

The paper analyzes longitudinal metabolomic changes of biogenic amines in plasma and CSF of TgF344 AD rats and WT controls, revealing sex- and age-specific differences.

Fluids and Barriers of the CNS · May 9, 2026Peer-reviewedSystems Biology

Metabolic Alteration in Oxylipins and Endocannabinoids Point to an Important Role for Soluble Epoxide Hydrolase and Inflammation in Alzheimer's Disease - Finding from Alzheimer's Disease Neuroimaging Initiative.

Kamil Borkowski, Chunyuan Yin, Alida Kindt, Nuanyi Liang, Elizabeth C. M. de Lange, Colette Blach, John W. I. Newman, Rima F Kaddurah-Daouk, Thomas Hankemeier, the Frontotemporal Lobar Degeneration Neuroimaging Initiative

The paper analyzes metabolites in AD patients to show inflammation and sEH dysregulation, with sex and disease stage differences, and identifies markers of disease progression and cognitive resilience.

Alzheimer s Research & Therapy · Jan 7, 2026Peer-reviewedNeuroscience

Lipidomic Fingerprints Reveal Sex-, Age-, and Disease-Dependent Differences in the TgF344-AD Transgenic Rats

Chunyuan Yin, Alida S. D. Kindt, Amy C. Harms, Robin Hartman, Thomas Hankemeier, Elizabeth C. M. de Lange

The paper identifies age, sex, and disease-dependent lipidomic changes in TgF344-AD rats, showing similarities to human lipid profiles and developing predictive models for AD.

Metabolomics · Dec 1, 2025Peer-reviewedSystems Biology