Loss of either RASSF1A alone or in combination with Caveolin-1 inhibition is associated with different premalignant histopathological alterations in the mammary glands of transgenic mice
Cristina L. Cotarelo, Hanna T. Weber, Sven Roßwag, Tabea Wagner, Ina Schaefer, Jonathan Paul Sleeman, Sonja Thaler
The paper investigates the effects of RASSF1A and Caveolin-1 loss on mammary gland histopathology in mice, finding distinct premalignant changes with single or combined gene inactivation.
bioRxiv · Jul 15, 2026 · PreprintCancer Biology