Coordinated network of T cells and antigen presenting cells regulate tolerance to food
Anna Rudnitsky, Hanna Oh, Maya Margolin, Bareket Dassa, Inbar Shteinberg, Liat Stoler‐Barak, Ziv Shulman, Ranit Kedmi
The paper identifies RORγt+ antigen-presenting cells as the exclusive inducers of food-specific regulatory T cells, which interact with cDC1 to regulate CD8β T cell responses in the intestine.
Nature · May 27, 2025Peer-reviewedImmunology