CCT-217: A Landmark Gene Silencing Therapeutic for Weight Loss That Enhances Lean Mass Composition, Reduces Visceral, Subcutaneous Fat and Restores Metabolic Health in Obesity through Browning
CCT-217, an siRNA therapy targeting CB1R and ZFP423, reduces body weight and visceral fat while preserving lean mass and improving metabolic health in obese mice.
bioRxiv · Dec 30, 2024 · PreprintPharmacology & Toxicology