Cell specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems
Jamie C. Moffa, India N. Bland, Jessica R. Tooley, Vani Kalyanaraman, Monique R. Heitmeier, Meaghan C. Creed, Bryan A. Copits
The paper develops a CRISPR/Cas9 gene editing strategy using a single AAV vector and Cre-dependent Cas9 in mice to enable cell-type specific editing and tool delivery in the nervous system.
eNeuro · Jun 13, 2024Peer-reviewedNeuroscience