Intra-nanoparticle Drug-protein Interactions Mediate Sequential Therapeutic Release
Huibin Chang, Anup Dey, Tengfei Ma, Ingrid Oprea, Rachel Y. Zhang, Sufeng Zhang
This study develops a drug delivery system using HSA nanoparticles where vancomycin modulates drug release kinetics through interactions with albumin's secondary structure.
bioRxiv · Jun 17, 2026 · PreprintBioengineering