Author

Irhum Shafkat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:E. coli· 1 Approach:large language model· 1 Organism:multiple species· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Alexander DerryiD· 1 shared Alexander W. RivesiD· 1 shared Carolyn Kim· 1 shared Chetan Mishra· 1 shared Deniz OktayiD· 1 shared Halil AkiniD· 1 shared Jonathan DeatoniD· 1 shared Jun Gong· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Alexander DerryORCID

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1 paper

Recent·Most cited

Simulating 500 million years of evolution with a language model

Thomas Hayes, Roshan Rao, Halil Akin, Nicholas Sofroniew, Deniz Oktay, Zeming Lin, Robert Verkuil, Vincent Q. Tran, Jonathan Deaton, Marius Wiggert, Rohil Badkundri, Irhum Shafkat, Jun Gong, Alexander Derry, Raul S. Molina, , Alexander W. Rives

ESM3, a 98-billion-parameter multimodal protein language model tokenized across sequence, structure, and function, designs a bright green fluorescent protein at 58% sequence identity to known fluorescent proteins.

Science · Jan 16, 2025Peer-reviewedSynthetic Biology✦ In-depth digest