Author

Vincent Q. Tran

Arc Research InstituteORCID 0009-0005-2705-5305Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

Patrick D. HsuiD· 3 shared April PawlukiD· 2 shared Liam J. BartieiD· 2 shared Silvana KonermanniD· 2 shared Alessandra SclipiD· 1 shared Alexander DerryiD· 1 shared Alexander MarsoniD· 1 shared Alexander W. RivesiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBioengineering

Patrick D. HsuORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioengineeringNature CommunicationsPeer-reviewedApr 24, 2026

A combinatorial domain screening platform reveals epigenetic effector interactions for transcriptional perturbation

Hyungseok C. Moon, Michael H. Herschl, Alessandra Sclip…·Patrick D. Hsu

The paper introduces COMBINE, a platform that screens epigenetic effector domain pairs to identify synergistic and antagonistic interactions, revealing new mechanisms for transcriptional regulation.

9 citationstop 2%

humanChIP-seq

𝕏 PostBluesky

BioengineeringNature BiotechnologyPeer-reviewedNov 6, 2025

Site-specific DNA insertion into the human genome with engineered recombinases

Alison Fanton, Liam J. Bartie, Juliana Q. Martins…·Patrick D. Hsu

This study engineers recombinases to improve DNA insertion efficiency and specificity in human cells, achieving 53% integration and 97% genome-wide specificity.

29 citationstop 1%

humanexperimental assay

𝕏 PostBluesky

Synthetic BiologySciencePeer-reviewedJan 16, 2025

✦ In-depth digest

Simulating 500 million years of evolution with a language model

Thomas Hayes, Roshan Rao, Halil Akin…·Alexander W. Rives

ESM3, a 98-billion-parameter multimodal protein language model tokenized across sequence, structure, and function, designs a bright green fluorescent protein at 58% sequence identity to known fluorescent proteins.

941 citationstop 1%

multiple speciesE. coli

𝕏 PostBluesky