Inhibition of the Notch signal transducer CSL by Pkc53E-mediated phosphorylation to fend off parasitic immune challenge in Drosophila
Sebastian Deichsel, Lisa Frankenreiter, Johannes Fechner, Bernd Martin Gahr, Mirjam Zimmermann, Helena Mastel, Irina Preis, Anette Preiss, Anja C. Nagel
The paper shows that Pkc53E-mediated phosphorylation of Su(H) inhibits Notch signaling, enabling Drosophila to mount an effective immune response against parasitic wasps.
eLife · Nov 6, 2024Peer-reviewedDevelopmental Biology