Author

Isabella E. Mack

William & Mary

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Petra Anne LeviniD· 1 shared Sarah E. AndersoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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1 shared paperMicrobiology

Petra Anne LevinORCID

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1 paper

Recent·Most cited

Enzymatic Activity of PBP1B Compensates for β-lactam Mediated Inhibition of PBP2 in Cells Overproducing ppGpp

Sarah E. Anderson, Isabella E. Mack, Petra Anne Levin

This paper shows that overproduction of ppGpp in E. coli increases resistance to β-lactam antibiotics targeting PBP2 by enhancing PBP1B activity through LpoB activation.

bioRxiv · Jun 12, 2025 · PreprintMicrobiology