Enzymatic synthesis of isotopically labeled hydrogen peroxide for mass spectrometry-based applications
Margaret Hoare, Ruiyue Tan, Isabella Militi, Kevin A. Welle, Kyle Swovick, Jennifer R. Hryhorenko, Sina Ghaemmaghami
The paper describes a method to enzymatically synthesize isotopically labeled hydrogen peroxide (H218O2) for use in mass spectrometry to accurately measure methionine oxidation levels.
Journal of the American Society for Mass Spectrometry · Oct 4, 2024Peer-reviewedBiochemistry