CASM potentiates STING-driven NFκB signaling in immune cells
Isis Benoit-Lizon, Cassandre Pignol, Kirsty M. Hooper, Caroline Truntzer, Abdelmnim Radoua, Ludivine Dal Zuffo, Julie Lucas, Quentin Frenger, Emy Ponsardin, Clarisse Cornebise, Isabelle Cantaloube, Ameetha Ratier, Romain Aucagne, François Hermetet, Sayyed Hamed Shahoei, , Lionel Apétoh
The paper investigates the role of CASM in STING signaling, finding that CASM enhances NFκB-driven TNF production while autophagy exerts negative feedback on STING pathways.
bioRxiv · Jan 24, 2026 · PreprintCell Biology