Author

Isobel Bolger

NYU Langone Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hemali P. PhatnaniiD· 2 shared Kathryn O’NeilliD· 2 shared Molly HammelliD· 2 shared Oliver H. TamiD· 2 shared Regina Shaw· 2 shared Christopher A. JacksoniD· 1 shared Cláudio Gouveia RoqueiD· 1 shared Colin M. SmithiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersGenomics

Hemali P. PhatnaniORCID

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2 papers

Recent·Most cited

TDP-43 dysfunction leads to the accumulation of cryptic transposable element-derived exons, crypTEs, in iPSC derived neurons and ALS/FTD patient tissues

Isobel Bolger, Regina Shaw, Oliver H. Tam, Cláudio Gouveia Roque, Christopher A. Jackson, Kathryn O’Neill, Colin M. Smith, Hemali P. Phatnani, Karthick Natarajan, Molly Hammell

This study identifies TDP-43-dependent cryptic gene-TE fusions (crypTEs) in neurons and ALS/FTD tissues, showing their association with altered gene expression and potential pathogenic effects.

bioRxiv · Jan 9, 2026 · PreprintGenomics

ALS molecular subtypes are a combination of cellular, genetic, and pathological features learned by deep multiomics classifiers

Kathryn O’Neill, Regina Shaw, Isobel Bolger, Oliver H. Tam, Hemali P. Phatnani, Molly Hammell

This study introduces DANcer, a deep learning classifier that identifies robust ALS molecular subtypes across bulk and single-cell datasets, showing they correlate with clinical features and cellular mechanisms.

Cell Reports · Mar 1, 2025Peer-reviewedGenomics