Author

Cláudio Gouveia Roque

New York Genome CenterORCID 0000-0003-3768-9633Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christopher A. JacksoniD· 2 shared Hemali P. PhatnaniiD· 2 shared Aidan C. DalyiD· 1 shared Alejandro LuarteiD· 1 shared André Weber· 1 shared Andrea Cristina Paula-LimaiD· 1 shared Andrés CouveiD· 1 shared Ankush ChakrabortyiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Christopher A. JacksonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GenomicsCellPeer-reviewedAug 4, 2026

Distinct Cellular Phenotypes of Language and Executive Decline in Amyotrophic Lateral Sclerosis

Joana Petrescu, Cláudio Gouveia Roque, Christopher A. Jackson…·Hemali P. Phatnani

The paper maps cognitive impairments in ALS by integrating spatial and single-nucleus transcriptomics, revealing distinct cellular and molecular patterns in language and executive dysfunction.

4 citationstop 2%

humanspatial transcriptomics

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GenomicsbioRxivPreprintJan 9, 2026

TDP-43 dysfunction leads to the accumulation of cryptic transposable element-derived exons, crypTEs, in iPSC derived neurons and ALS/FTD patient tissues

Isobel Bolger, Regina Shaw, Oliver H. Tam…·Molly Hammell

This study identifies TDP-43-dependent cryptic gene-TE fusions (crypTEs) in neurons and ALS/FTD tissues, showing their association with altered gene expression and potential pathogenic effects.

2 citations

humanscRNA-seq

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NeurosciencebioRxivPreprintAug 11, 2024

Local synthesis of Reticulon-1C lessens the outgrowth of injured axons and Spastin activity

Alejandro Luarte, Javiera Gallardo, Daniela Corvalán…·Andrés Couve

This study identifies Reticulon-1C as a locally synthesized axonal protein that modulates microtubule dynamics and axon outgrowth by regulating Spastin activity.

DOI 10.1101/2024.08.11.607514

mousebulk RNA-seq

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