Ratiometric transcriptional activation by protein degradation
Melissa Anne Gray, Katelyn L. Randal, J Co, Michelle T. Tang, Athena Xue, Sophia W. Chen, Hlib Razumkov, Qusay Q Omran, David E. Solow-Cordero, Jeonghye Yu, Stephanie A. Robinson, Cara Ann Starnbach, Nathanael S. Gray, Steven M. Corsello, Steven M. Banik
This paper introduces ratiometric transcriptional activation to detect protein abundance changes by converting protein degradation into gene expression outputs in live cells.
Cell · Sep 1, 2026Peer-reviewedSynthetic Biology