Widespread roles of Trypanosoma brucei ATR in nuclear genome function and transmission are linked to R-loops
J. A. Black, K. Crouch, E. M. Briggs, L. Lemgruber, C. Lapsley, L. R. O. Tosi, J. C. Mottram, R. McCulloch
This study shows that ATR in Trypanosoma brucei is involved in genome maintenance, R-loop regulation, and chromosome segregation, despite DNA damage and continued cell division after ATR depletion.
bioRxiv · Sep 9, 2021 · PreprintCell Biology