Spreading of a mycobacterial cell surface lipid into host epithelial membranes promotes infectivity
C. Cambier, S. Banik, J. A. Buonomo, C. Bertozzi
This study shows that PDIM from mycobacteria spreads into host epithelial membranes, inhibiting TLR activation and enhancing infectivity, with statins reducing this spread and offering protection.
bioRxiv · Jun 30, 2020 · PreprintMicrobiology