High resolution studies of DNA lesion bypass by human DNA polymerase δ holoenzymes
R. L. Dannenberg, J. A. Cardina, K. G. Pytko, M. Hedglin
This study quantitatively examines how human DNA polymerase δ holoenzymes handle DNA lesions during replication, showing they can replicate lesions and their effects depend on lesion type and proofreading.
bioRxiv · Jun 30, 2022Biochemistry