Matrix metalloproteinase-2 mediates ribosomal RNA transcription by cleaving nucleolar histones
M. A. M. Ali, J. A. Garcia-Vilas, C. R. Cromwell, B. P. Hubbard, M. J. Hendzel, R. Schulz
This study identifies MMP-2 as a nucleolar enzyme that cleaves histone H3 to enhance rRNA transcription and promote cell proliferation.
bioRxiv · Feb 21, 2020Cell Biology