Author

J. A. Karim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

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Approach:experimental assay· 1

Frequent Co-Authors

A. A. Pioszak· 1 shared A. Dickson· 1 shared J. Lennon· 1 shared K. M. Babin· 1 shared P. H. Gordon· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

A. A. Pioszak

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1 paper

Recent·Most cited

Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of theadrenomedullin2 G protein-coupled receptor

K. M. Babin, J. A. Karim, P. H. Gordon, J. Lennon, A. Dickson, A. A. Pioszak

The paper identifies AM2/IMD as a slow off-rate agonist for the AM2R receptor, showing prolonged cAMP signaling and defining the molecular mechanism of kinetic selectivity.

bioRxiv · Jan 13, 2023 · PreprintBiochemistry