Author

J. A. Soler

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Biophysics· 1

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Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Singh· 1 shared J. Lauer· 1 shared M. Jahnel· 1 shared M. Zerial· 1 shared S. Thutupalli· 1 shared S. W. Grill· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

A. Singh

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1 paper

Recent·Most cited

GTPase-dependent cyclic flexibility transitions drive the two-component EEA1-Rab5 molecular motor

A. Singh, J. A. Soler, J. Lauer, S. W. Grill, M. Jahnel, M. Zerial, S. Thutupalli

This study shows that Rab5 and EEA1 form a two-component molecular motor using GTP hydrolysis to drive cyclic flexibility transitions that perform mechanical work.

bioRxiv · Jul 18, 2022 · PreprintBiophysics