Tuneable hydrogel stiffness in a 3D in vitro model induces epithelial to mesenchymal transition in MCF7 but not MDA-MB-231 breast cancer cells
J. A. Wise, M. J. Currie, T. B. Woodfield, K. S. Lim, E. Phillips
This study shows that MCF7 breast cancer cells undergo epithelial-to-mesenchymal transition in stiff hydrogels, while MDA-MB-231 cells do not, highlighting the role of matrix stiffness in cancer progression.
bioRxiv · Jun 29, 2023 · PreprintCancer Biology